Specific Environmental Exposures that Increase Asbestos Related Diseases

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There have been a range of epidemiologic studies examining the link between asbestos particles and mesothelioma cancer. Typically it can be a tough task to identify the specific environmental exposures that increase the speed of asbestos connected diseases. One interesting study is named, “Asbestos bodies in bronchoalveolar lavage fluid and in lung parenchyma.” By Sebastien P, Armstrong B, Monchaux G, and Bignon J - Am Rev Respir Dis. 1988 Jan;137(1):75-8. - McGill University, College of Occupational Health, Mud Disease Research Unit, Montreal, Quebec, Canada. Here is an excerpt:

“Numerical concentrations of asbestos bodies (AB) were measured by light microscopy both in samples of bronchoalveolar lavage (BAL) fluid and in samples of lung parenchyma from sixty nine patients with suspected asbestos-related diseases who had had lavages and later open lung biopsies or autopsies. Objectives were to check the recovery of pulmonary AB by BAL and the flexibility of BAL concentrations to predict parenchymal concentrations. BAL and parenchymal concentrations were each unfold over 6 orders of magnitude and were positively correlated (r = 0.seventy four between logarithmic values). It's believed that, by a process of progressive elution, AB firmly adherent to the alveolar wall become suspended in BAL fluid; such suspended bodies represent roughly a pair of% of all the bodies stored in the portion of lung lavaged. Recovery is associated with nice interindividual variations. When a measured BAL concentration exceeds 1 AB/ml, it will be quite confidently predicted, but, that the parenchymal concentration is in more than one,000 AB/g and that the patient has experienced a nontrivial asbestos exposure.”

Another attention-grabbing study is called, “Mesothelioma in pet dogs related to exposure of their house owners to asbestos.” By Glickman LT, Domanski LM, Maguire TG, Dubielzig RR, and Churg A. - Environ Res. 1983 Dec;32(two):305-13.

Here is an excerpt: “Pet dogs with spontaneous mesothelioma were used to spot environmental exposures that might increase their owner's risk of asbestos-related disease. These animals share man's domicile setting, nonetheless do not enjoys activities (e.g., smoking, operating) which confound interpretation of epidemiologic studies. Eighteen histologically confirmed canine mesotheliomas were diagnosed at the Veterinary Hospital of the University of Pennsylvania, Philadelphia, from April 1977 to December 1981. Sixteen owners of cases and 32 homeowners of age, breed, and sex-matched controls were interviewed to work out their occupation and medical history and their dog's medical history, life style, diet, and exposure to asbestos. An asbestos-related occupation or hobby of a household member and use of flea repellents on the dog were considerably related to mesothelioma. Additionally, there was a trend indicating an increased risk of mesothelioma with an urban residence. L!
ung tissue from three dogs with mesothelioma and one dog with squamous cell carcinoma of the lung had higher levels of chrysotile asbestos fibers than lung tissue from management dogs. These findings indicate that well-designed epidemiological studies of spontaneous tumors in pet animals may provide insight into the role of environmental factors in human cancers and function a valuable sentinel model to spot environmental health hazards for humans.”

If you found either of those excerpts helpful, you ought to read them in their entirety.

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Carey Howard has been writing articles online for nearly 2 years now. Not only does this author specialize in Diseases, you can also check out his latest website about: Honeywell Home Security Which reviews and lists the best wireless home security alarms

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